Opportunity Information: Apply for HT942526TSCRPCTRA
The FY26 Tuberous Sclerosis Complex Research Program (TSCRP) Clinical Translational Research Award (CTRA) is a discretionary grant opportunity from the Department of the Army, administered through USAMRAA, that aims to push strong tuberous sclerosis complex (TSC) research closer to real-world clinical use. The central purpose of the award is to support studies that translate promising and well-supported preclinical and/or clinical findings into applications that can meaningfully improve patient care. In practical terms, this means projects should be positioned to advance toward clinical application in areas such as TSC diagnosis, prognosis, or treatment, rather than remaining purely exploratory or early-stage basic research.
A notable feature of this funding mechanism is that it is designed to accommodate team science through multiple Principal Investigators (PIs). The application process is structured so that only the initiating PI submits the pre-application, but all PIs involved are required to submit full applications if invited to proceed. Partnering PI applications are not identical copies of the initiating PI package; instead, they are abbreviated submissions focused on the specific portion of the overall project that each partner leads. This structure is intended to support multi-institutional or multidisciplinary collaborations while keeping accountability clear for each distinct component of the work.
There is also an important administrative dependency built into the multi-PI approach: associated applications are linked, and the program warns that all related applications for a given research project may be withdrawn if either the initiating PI or any partnering PI application is rejected or administratively withdrawn. This makes coordination between collaborators essential, since issues in one linked application can affect the entire project’s ability to be considered.
Key opportunity details include the funding opportunity title "DoW Tuberous Sclerosis Complex, Clinical Translational Research Award" and the opportunity number HT942526TSCRPCTRA. The funding instrument is a grant, and the activity category is Science and Technology and other Research and Development (CFDA 12.420). Eligibility is listed as unrestricted, suggesting a broad applicant pool may apply, subject to standard federal and program-specific requirements. The posted closing date is August 6, 2026, and the program anticipates making about two awards. The award ceiling is not specified in the provided listing, so applicants would need to consult the full announcement and program guidelines for budget limits, allowable costs, and any cost-sharing expectations.Apply for HT942526TSCRPCTRA
- The Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoW Tuberous Sclerosis Complex, Clinical Translational Research Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on 2026-05-05.
- Applicants must submit their applications by 2026-08-06. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted.
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FY26 TSCRP Clinical Translational Research Award (CTRA) - FAQs
1) What is the FY26 Tuberous Sclerosis Complex Research Program (TSCRP) Clinical Translational Research Award (CTRA)?
The FY26 TSCRP CTRA is a discretionary Department of the Army grant opportunity, administered through USAMRAA, focused on moving strong tuberous sclerosis complex (TSC) research closer to real-world clinical use.
2) What is the main goal of this award?
The central purpose is to support studies that translate promising and well-supported preclinical and/or clinical findings into applications that can meaningfully improve patient care. Projects should be positioned to advance toward clinical application, rather than remaining purely exploratory or early-stage basic research.
3) What types of research are a good fit for this opportunity?
Projects intended to translate prior results into clinical application, including work advancing toward TSC-related diagnosis, prognosis, or treatment. The emphasis is on translational movement toward clinical use, grounded in well-supported preclinical and/or clinical findings.
4) Is early-stage or purely exploratory basic research a fit for this award?
Based on the description provided, this mechanism is not intended for purely exploratory or early-stage basic research. The expectation is that the project is ready to move toward clinical application.
5) Who is offering and administering the grant?
The opportunity is from the Department of the Army and is administered through USAMRAA.
6) What is the official funding opportunity title?
The listed title is "DoW Tuberous Sclerosis Complex, Clinical Translational Research Award."
7) What is the opportunity number?
The opportunity number is HT942526TSCRPCTRA.
8) What type of funding instrument is this?
The funding instrument is a grant.
9) What is the activity category and CFDA number?
The activity category is Science and Technology and other Research and Development, with CFDA 12.420.
10) Who is eligible to apply?
Eligibility is listed as unrestricted, indicating a broad pool of applicants may apply, subject to standard federal requirements and any program-specific requirements included in the full announcement.
11) Are multiple Principal Investigators (PIs) allowed?
Yes. A notable feature of this award is that it is designed to accommodate team science through multiple PIs.
12) How does the multi-PI pre-application process work?
Only the initiating PI submits the pre-application. If the project is invited to proceed, all PIs involved are required to submit full applications.
13) Do partnering PIs submit the same full application as the initiating PI?
No. Partnering PI applications are abbreviated submissions and are not identical copies of the initiating PI package. Each partner PI submission focuses on the specific portion of the overall project that the partner leads.
14) Why does the opportunity use an initiating PI and partnering PI structure?
The described structure is intended to support multi-institutional or multidisciplinary collaborations while keeping accountability clear for each distinct component of the work.
15) Are the multiple PI applications linked to each other?
Yes. The program indicates that associated applications are linked for a given research project.
16) What is the administrative risk of having linked initiating and partnering PI applications?
The program warns that all related applications for a given research project may be withdrawn if either the initiating PI or any partnering PI application is rejected or administratively withdrawn. This means coordination and compliance across all linked submissions is critical.
17) What happens if a partnering PI application is administratively withdrawn?
Based on the stated dependency, all related applications for the project may be withdrawn if any partnering PI application is rejected or administratively withdrawn.
18) What is the posted closing date?
The posted closing date is August 6, 2026.
19) How many awards does the program expect to make?
The program anticipates making about two awards.
20) What is the maximum award amount (award ceiling)?
The award ceiling is not specified in the provided listing. Applicants would need to consult the full announcement and program guidelines for budget limits and related details.
21) Are allowable costs, budget limits, or cost-sharing requirements included in the provided information?
No. The provided listing notes that applicants should consult the full announcement and program guidelines for budget limits, allowable costs, and any cost-sharing expectations.
22) What should applicants do if they need detailed budget rules or cost guidance?
Refer to the full announcement and program guidelines, since the provided listing does not include an award ceiling, allowable cost details, or cost-sharing expectations.
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